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New UB Medical School Design Revealed

April 10, 2013 by BNMCin Allentown, Member Institution(s), News

The University at Buffalo (UB) unveiled the HOK design for the new School of Medicine and Biomedical Sciences building to be constructed atop the NFTA Allen/Medical Campus station on the Buffalo Niagara Medical Campus.

Since winning the international design competition for the medical school concepts last year, HOK has worked closely with UB officials, the SUNY Construction Fund and community groups to develop the design best suited to the needs of the medical school while strengthening connections with the surrounding community. The design process is still underway, but is expected to be finalized within the next few months. The groundbreaking for the 7-story, more than 500,000-square-foot school is scheduled for the fall of 2013. The medical school will be one of the largest buildings constructed recently in the region when it officially opens in 2016.

Expected to bring an additional 2,000 faculty, staff and students to the Medical Campus, the steel-framed, state-of-the-art facility will feature a 6-story, light-filled glass atrium. The building’s façade will be clad with a high-performance terra cotta rainscreen and a glass curtain wall system that will bring daylight deep into the building. A convenient facility amenity will include bridges connecting to the two L-shaped buildings, the soon-to-be-built John R. Oishei Children's Hospital and Conventus medical office building.

Serving as the building’s main interior “avenue,” there will be an atrium that will provide naturally illuminated by skylights and two glass walls, one along Washington Street and the other toward Allen Street.

Floor layout:

Floors 1 & 2: Multipurpose educational and community spaces for medical school and community outreach programs, such as the UB mini-medical school and other public health initiatives. The goal is to make the building’s public spaces highly accessible.

Floors 3, 4 & 5: Core research facilities as well as wp-contentroximately 150,000-square-foot of state-of-the art, easily configurable research laboratories for faculty in the basic sciences.

Floor 6: Advanced and specialized medical education facilities in the U.S., such as an expanded patient care simulation center, which will include the Behling Simulation Center, currently located on UB’s South Campus.
Floor 7: Gross anatomy facilities.

The medical school’s administrative offices and academic departments will be located on floors 3-7. It will also house a surgical simulation center where medical students can conduct surgeries in a simulated operating room. A complementary robotic surgery simulation center will train students and physicians in the latest remotely controlled robotic surgery technologies.

Aligning with key objectives from the UB 2020 strategic plan, the medical school will help create of a world-class medical school, increase recruitment of outstanding scientists, physician-scientists and clinicians to the university and transform the region into a major destination for innovative medical care and research.

“The new design allows us to grow our class size from 140 to 180, educating more physicians, many of whom will practice in the region,” said Michael E. Cain, MD, vice president for health sciences at UB and dean of the medical school. “It allows UB to hire more talented faculty, bringing to this community much-needed clinical services and medical training programs.”

The new design also provides the most efficient layout for state-of-the-art medical education and research as it looks to receive LEED gold certification. A pedestrian passageway will extend through the building between Main and Washington Streets, leading to the Allen Street Western Gateway. To further promote alternative transportation modes, the passageway is deliberately aligned with a proposed Allen Street pedestrian extension from Washington to Michigan Streets, which will feature a bike share facility.

Cain also stated that “faculty conducting scientific and translational research will be in close proximity to faculty performing clinical care in the hospitals” and that the new design will establish “a complete continuum from discovery to patient care on one campus and in modern facilities expressly designed to efficiently maximize the medical school’s primary missions of education, clinical service and research.”

With the medical school so close to major teaching hospitals like Kaleida Health's Buffalo General Medical Center and Roswell Park Cancer Institute and research facilities like the Clinical Translational Research Center, UB will be made into a strong academic and health care contender, much like Cleveland Clinic and the University of Pittsburgh Medical Center.

For UB's downtown campus, the medical school will help create a vibrant, urban, mixed-use district seamlessly connected to the surrounding Allentown and Fruit Belt neighborhoods and other downtown communities. The $375 million medical school is partly funded by the NYSUNY 2020 legislation and private donations.

Read coverage about the medical school design unveiling below:

New UB Medical School is Designed to be an Integral Part of its Community

UB Unveils Med School Design (More Images)

UB Unveils New Downtown Medical Facility Design (With Photos)

UB Unveils School of Medicine Design

UB Unveils Design for Downtown Medical School: Building to be “Gateway”

UB Offers Images of Future Medical School

*Pictures retrieved from the University at Buffalo/HOK

*YouTube video created by the University at Buffalo

Light Smokers Benefit from Nicotine-Replacement Medications

April 10, 2013 by BNMCin Campus-wide, Community, Homepage, Member Institution(s), News, Research

75% of smokers in Roswell Park-led study said offer of free cessation medication ‘very important’ to quit effort

Light daily smokers, those who smoke fewer than 10 cigarettes per day, have greater success quitting when provided stop-smoking medications and assisted by counselors. Those are the key conclusions of research conducted by scientists at Roswell Park Cancer Institute (RPCI) and the Medical University of South Carolina and published in the latest issue of Nicotine and Tobacco Research.

While the number of light smokers is increasing, most studies have focused on the benefits of counseling and nicotine-replacement therapy (NRT) for moderate and heavy smokers. This study found that light smokers who contacted a telephone quitline are typically interested in using NRT and achieve higher quit rates than those who were not offered NRT.

“While many studies have demonstrated the efficacy of nicotine medications for smoking cessation, very few have examined these questions in lighter smokers, as we have done,” says Martin Mahoney, PhD, MD, Associate Professor in the departments of Health Behavior and Medicine at RPCI and senior study author. “A unique strength of this study is the use of an experimental design implemented in a real world community setting of a state quitline.”

The study evaluated long-term quitting success among 1,365 adult tobacco users who smoked less than 10 cigarettes daily and who contacted the New York State Smokers’ Quitline for assistance between January and July 2010. All smokers received two calls from trained stop-smoking counselors, and about half of the smokers were provided with stop-smoking medications.

Nearly all the light smokers offered the free nicotine medications wanted the medications, and 75% of smokers rated the offer of a free supply of NRT as very important to their quit effort. The quit rates measured at seven months were 20% higher in the group offered the NRT (33%) compared with those who received only counseling (27.2%).

“These findings demonstrate that low-level daily smokers are interested in and benefit from using NRT when they make a quit attempt,” said Laurie Krupski, first author on the study and a Training and Development Coordinator in the Department of Health Behavior at RPCI.

“Smoking cessation is a highly cost-effective intervention because the health consequences of smoking are enormously expensive and compound over time. This study demonstrates that quitline counseling in combination with NRT is a good return on investment,” said K. Michael Cummings, PhD, MPH, Professor, Department of Psychiatry and Behavior Sciences, Medical University of South Carolina.

This work was supported in part by the New York State Department of Health and by the National Cancer Institute’s Cancer Center Support Grant to RPCI (P30CA016056).

The study, “Nicotine Replacement Therapy Distribution to Light Daily Smokers Calling a Quitline,” is available at http://goo.gl/dUiio.

Annie Deck-Miller, RPCI Senior Media Relations Manager; annie.deck-miller@roswellpark.org; 716.845.859

Buffalo Niagara Medical Campus, Inc. Secures Nearly $400,000 to Support Alternative Transportation Efforts for 12,000 Employees

April 8, 2013 by BNMCin Campus-wide, Employees, Parking, Transportation

FOR IMMEDIATE RELEASE
Monday, April 8, 2013

For more information, contact:

Kari Bonaro, Director of Communications
kbonaro@bnmc-old.local or 716.218.7157

Buffalo Niagara Medical Campus, Inc. Secures Nearly $400,000 to Support Alternative Transportation Efforts for 12,000 Employees

Initiatives Designed to Reduce Employees Driving By Themselves to Work, Ensures Ample Patient Parking

(Buffalo, NY) – The Buffalo Niagara Medical Campus, Inc. (BNMC, Inc.) has secured $393,432 through a combination of cost-shared research agreements from the New York State Energy Research and Development Authority (NYSERDA) and the New York State Department of Transportation (NYSDOT), and two separate grants from the Federal Transit Authority (FTA) Job Access-Reverse Commute (JARC) program over the past two years to advance alternative transportation efforts on the Buffalo Niagara Medical Campus and surrounding neighborhoods.

The Buffalo Niagara Medical Campus is a 120-acre home to the region’s top clinical, research, and medical education institutions, including Kaleida Health, Roswell Park Cancer Institute, and the University at Buffalo, and nearly 60 private sector companies. More than 12,000 people come to work at the Medical Campus every day, an increase from 8,500 in 2008. An additional two million square feet of clinical, research and development space has been added in the past few years, with another two million square feet (and 5,000 more employees) slated to come online in the next five years.

This rapid growth has encouraged the BNMC, Inc., the not-for-profit charged with coordinating the sustainable planning, development, and enhancement of the growing urban campus, to get creative with the diverse ways they can encourage people to access the campus.

Some of these efforts include:

Launching GO BNMC, a campus-wide movement to support smart commuting;
Forming a transportation management association, a stakeholder group of both Medical Campus and community partners;
Strengthening partnerships with Buffalo CarShare and BikeShare and GObike Buffalo;
Conducting a mitigation study helping prioritize complete streets infrastructure projects around the Medical Campus to make the area more accessible by modes other than cars;
Forging a continued relationship with the NFTA that has already resulted in route changes and additions to better serve the BNMC population; and
Collaborating with other businesses and partners off of the Medical Campus, such as the Buffalo Sabres, to develop mutually beneficial transportation options.
Increasing the number of neighborhood residents employed at BNMC institutions by better informing them of the career and training opportunities available on and around the Medical Campus.

“Creating an accessible destination, including ample parking, for the more than one million annual patients and visitors is our first priority,” according to Bill Smith, Director of Campus Access. “To make this hwp-contenten, we realized we have to reduce the number of employees driving by themselves to work. It starts with changing behaviors. We were extremely fortunate that NYSERDA came on as a partner early on in this process. They’ve really enabled us to get our initiative off the ground and find additional funding partners to expand our offerings, including the federally-funded Guaranteed Ride Home program we will launch next month.”

At the beginning of 2012, wp-contentroximately 88 percent of the employees on the Buffalo Niagara Medical Campus drive to work by themselves. However, surveys have shown that about 75 percent of employees would consider ridesharing and taking public transit if a ride home was guaranteed in an emergency. Another 50 percent of employees said that financial incentives and rewards would help make a difference in changing their commuting behavior.

“The alternative transportation options being offered to Buffalo Niagara Medical Campus employees complement the innovative transportation programs the state is utilizing to reduce the consumption of fossil fuel,” said Francis J. Murray Jr., President and CEO, NYSERDA. “Governor Cuomo has stressed that public-private partnerships like this one are the cornerstone to creating a more robust economy and a sustainable environment.”

For this incentive program, NYSERDA had partnered with the New York State Department of Transportation.

“By expanding the transportation options available to employees at the Buffalo Niagara Medical campus, we will enhance safety and mobility for thousands of commuters each day and improve their quality of life,” said Department of Transportation Commissioner Joan McDonald. “Under Governor Cuomo’s leadership, innovative partnerships like this one are making transportation improvements that have lasting benefits, improving highway safety, encouraging economic growth and protecting air quality and the environment.”

The BNMC, Inc. has set goals to reduce the percentage of employees driving to work by 13 percent over the next five years and up to 25 percent by the year 2030. Since launching the GO BNMC, an online alternative commuter toolkit, in September 2012, more than 360 employees have already signed up. BNMC, Inc. plans on at least doubling this number with a full scale marketing campaign coming this spring.

Providing as many quality transportation options as possible not only begins to help solve the looming employee parking challenge, it also supports the overall BNMC sustainability goal of ensuring employees have the ability to choose greener, healthier, and more affordable options to get to work.

A breakdown of the three grants include:

Transportation Management Association (TMA) and TDM Toolkit ($120,999 cost-shared research agreement through NYSERDA/NYSDOT ) This is for the establishment and first year activities of a Transportation Management Association (TMA) that works to advance the Transportation Demand Management (TDM) strategies of the BNMC. Members of the TMA include: BNMC, Inc., representatives from the Medical Campus institutions, NYSERDA, NYSDOT, NFTA, GBNRTC, BUDC, GoBike Buffalo and Buffalo Carshare. The TMA works to demonstrate the effectiveness of TDM strategies in reducing the number of vehicle miles traveled, enhancing alternative transportation options, and increasing mobility of the BNMC community. This is done through the development and production of marketing and educational materials and a web-based toolkit (online at www.gobnmc-old.local) to educate employees on their options, enhancing these transportation options, providing free and reduced NFTA transit passes to incentivize new riders, and free Buffalo CarShare and GoBike memberships.

Guaranteed Ride Home ($36,253 funded through FTA JARC ) The program will provide employees of the BNMC who do not drive alone to work with a timely and free means of transportation (i.e., taxi rides) in the event of a personal or family emergency, illness or unexpected employment-related delay, such as an unscheduled overtime. This program is designed to promote the use of transit, ridesharing, and alternative modes among BNMC employees by providing a safety net for those who do not drive to work.

Community Transportation Program ($206,180 funded through FTA JARC and $30,000 in local donations) This program is a collaborative effort between the BNMC, Inc., Buffalo CarShare, and GoBike Buffalo to facilitate and encourage the use of alternative transportation modes and public transit among employees on the BNMC and residents of the surrounding neighborhoods. In addition, the Program aims to increase the number of neighborhood residents employed at BNMC institutions by better informing them of the career and training opportunities available on and around the Medical Campus. This grant includes funding for a state-of-the art, secure, and dry bicycle storage facility located at the corner of Virginia and Ellicott Streets, designed by local architect Brad Wales and currently under construction.

About the Buffalo Niagara Medical Campus, Inc.

The Buffalo Niagara Medical Campus, Inc. (BNMC, Inc.) is the umbrella organization created in 2001 by the anchor institutions located within the Buffalo Niagara Medical Campus. The BNMC, Inc. is a not-for-profit organization that fosters conversation and collaboration among its member institutions, the 55+ private sector companies on the Medical Campus, 12,000 employees, and the community; coordinates activities related to sustainable planning, development and enhancement of its 120-acre space; and works to create a distinct, innovative environment that provides opportunities for entrepreneurship and active and healthy living. The BNMC, Inc. also works with partners throughout the community to develop healthier, greener, and more economical transportation solutions to meet the needs of our growing urban campus and the region as a whole.

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UB Helps to Launch Two Zimbabwe National Programs

April 5, 2013 by BNMCin Biotechnology Companies, Homepage, Life Sciences Companies, Member Institution(s), News, Research

UB Helps to Launch two Zimbabwe National Programs in Nanotechnology and HIV/AIDS Eradication

What does it take to launch two major international HIV/AIDS research initiatives involving the University at Buffalo (UB) and the University of Zimbabwe?

It requires attention to issues as diverse as working with government officials, choosing the right scientists, establishing ethics in research, training for quality control and good laboratory practices, transferring paper patient records into electronic formats and understanding how different cultures respond to serious illness and treatment.

And it requires face-to-face information exchange and planning.

A UB-led research team recently traveled to Zimbabwe to participate in a week-long program of workshops that included the formal launch of two Zimbabwe national programs: the Zimbabwe International Nanotechnology Center (ZINC) and the Zimbabwe Evidence-To-Action (ETA), an implementation project to eradicate HIV/AIDS in Zimbabwe.

With 14 percent of Zimbabwe's population living with HIV/AIDS and tuberculosis as a co-infection, the need for new drugs and new formulations of available treatments is crucial.

UB’s role in the ZINC partnership is to provide training to young scientists and students in Zimbabwe in multiple areas within nanotechnology. The trip to Zimbabwe included identifying research areas of common interest to Zimbabwe and prioritizing them according to the country’s needs.

UB has built a partnership with Zimbabwe over seven years through an NIH Fogarty International Center program.

Paras Prasad, PhD, SUNY Distinguished Professor in the Departments of Chemistry, Physics, Medicine and Electrical Engineering; Samuel P. Capen Chair of Chemistry and executive director of UB’s Institute for Lasers, Photonics and Biophotonics (ILPB), and Gene Morse, PharmD, professor and associate director of the UB Center of Excellence in Bioinformatics and Life Sciences headthe UB-ZINC collaboration.

“There was an incredible feeling of optimism and high energy toward both initiatives,” said Morse.

The week began with the second Zimbabwe National Nanotechnology Consultative Meeting on March 18 – 19.

Prasad, who will direct the international nanotechnology contributions for ZINC, gave the keynote address.

Morse, who will direct the international nanomedicine component of ZINC, presented the role that UB and the CoE will play in ZINC. Other participating UB faculty included Stanley Schwartz, MD, SUNY Distinguished Professor of Medicine and Peter Horvath, PhD, associate professor of exercise physiology and nutrition.

Background and details of ZINC were provided during presentations from the minister for science and technology development (MSTD), the Honorable Professor Heneri Dzinotyiweyi, UB alumnus, Chiedza Maponga, PharmD, technical director for nanotechnology (MSTD) and director of the UZ School of Pharmacy, and Josephat Zimba, Technical Consultant to the MSTD on nanotechnology. Additional presentations from Professor Levi Nyagura, UZ Vice Chancellor, and Professor David Simbi, CUT Vice Chancellor, described the leadership roles for their universities.

The week continued with a two-day workshop on March 20 – 21 for the ETA Project.

Hosted by the Ministry of Health and Child Welfare, the first day summarized:

Recent compelling data that provide the rationale for preventing HIV transmission through pre-exposure prophylaxis (PrEP) and treatment as prevention (TaSP)
The national statistics for prevention of mother-to-child transmission and pediatric HIV infection
HIV Prevention Trials Network (HPTN) 052 and the dramatic results obtained in discordant couples when the HIV-infected partner was treated early after infection leading to a reduced transmission rate
The need for a strategy to provide treatment to key populations with HIV infection including high risk groups such as prisoners, men who have sex with men, commercial sex workers and pregnant women.

At a concurrent workshop, Robin DiFrancesco, manager of the UB Clinical Pharmacology Quality Assurance Program (CPQA) and an AIDS International Training and Research Program (AITRP) mentor, provided lectures focused on building laboratory skills and bioanalytical method development.

In a second afternoon workshop, Kathleen Tooley, senior research support specialist in the UB Translational Pharmacology Research Core, and Education and Operations Administrator for CPQA and AITRP, and an AITRP mentor, moderated a group at the UZ College of Health Sciences to address challenges in research ethics and research administration for faculty and students who will conduct research within ETA.

Morse chaired the second day of the workshop and provided a presentation on the progress of the UB-UZ AITRP. Highlights included a review of the Training Advisory Group and the recently established Scientific Advisory Board, new research programs, nutritional and traditional medicine pharmacology, clinical pharmacology and healthcare informatics.

The second half of the morning program was chaired by Morse and focused on Bioinformatics and Health Information Technology (HIT) required for the ETA infrastructure in collaboration with the Zimbabwean health care system.

In the HIV Nutrition Pharmacology working group, Horvath and faculty and graduate students from the Departments of Pediatrics and Biochemistry discussed nutritional considerations for the ETA project.

Horvath also provided a seminar on March 25 for the UZ Departments of Pediatrics and Biochemistry titled “Nutritional Aspects of HIV Infection and Treatment.”

Morse was pleased with the results achieved during the visit.

“I was very proud that a country that has faced so many challenges to advancing the health of the nation and plan for scientific and economic growth was linked to the UB-UZ AITRP and the efforts that have been put forward over the last seven years.”

Morse said that the UB team’s visit contributed to two Zimbabwean national initiatives and conducted numerous sessions, workshops and small group meetings.

“The outcome created a new level of collaboration, reaching beyond university campuses to the highest levels of government ministries as well as community programs. This extensive spectrum of research and education programs has been built on the strong AITRP link between UZ and UB,” he said.

The events were jointly sponsored by the Zimbabwe Ministry of Health and Child Welfare; the University at Buffalo – University of Zimbabwe (UZ) AIDS International Training and Research Program (AITRP) and the UZ – UB International Pharmacotherapy Education and Research Initiative (IPERI).

Sara R. Saldi (UB); saldi@buffalo.edu; 716.645.4593

*Photo courtesy of UB: Breakfast meeting with UB-UZ AITRP fellows and families and UB's Gene Morse, Robin DiFrancesco (both upper left), Kelly Tooley (AITRP Education and Operations Coordinator) and Amy Moss (current UB HIV Resident and AITRP Mentor). Dr. Maponga is left next to Dr. Morse.

Try Transit This Spring with a Free 2-Week Metro Pass

April 4, 2013 by BNMCin Campus-wide, Employees, Homepage, Member Institution(s), Outreach, Transportation

With warm weather fast wp-contentroaching, there is no better time to join the growing number of BNMC and downtown workers who are commuting by Metro Rail and Bus.
Interested in seeing the benefits? GO BNMC is offering employees who work on the Buffalo Niagara Medical Campus free 2-week Metro passes that are good for unlimited Rail and Bus trips, providing the ideal opportunity to see if these commuting options are right for you.

The passes are only for employees on the BNMC who currently do not take transit to work, and can only be used between April 15^th and April 29^th.

To take advantage of this free offer, email gobnmc@bnmc-old.local or call 566-2316 and request your pass.

But hurry! Supplies are limited and passes will be available on a first-come basis.

Roswell Park Scientists Advance Findings About Novel, Low-Toxicity Anticancer Agent

April 2, 2013 by BNMCin Health care, Homepage, Member Institution(s)

New FL118 formulation may prove effective against colon, head/neck, mesothelioma, ovarian and pancreatic cancers

Researchers at Roswell Park Cancer Institute (RPCI) have found that a new formulation of a promising anticancer agent, the small chemical molecule FL118, is even more effective in controlling two types of cancer than a version reported in PLOS ONE six months earlier proved to be. Additional evidence also suggests that the agent may successfully treat other solid tumors as well.

In their previous research, a team led by Fengzhi Li, PhD, Associate Professor of Oncology in RPCI’s Department of Pharmacology and Therapeutics, demonstrated that FL118 eliminated human colon and head-and-neck tumors in animal models without relapse but was limited in that it could be delivered only by intraperitoneal (IP) administration. This new study, to be published in the April 8 issue of the American Journal of Translational Research, compares the earlier formulation of the agent to a new version that can also be administered intravenously, translating to much wider potential clinical wp-contentlication.

Comparing the antitumor efficacy and therapeutic index, or relative toxicity, of FL118 in its new intravenous (IV) formulation with the earlier form, the researchers found that maximum tolerated dose increased three- to seven-fold, depending on dosing schedule. While the original formulation contained Tween 80 or polysorbate 80, a solvent commonly included in drug formulations, the agent in its new composition is free of Tween 80, resulting in significantly lower toxicity.

FL118 is a targeted therapy that selectively inhibits the expression of four major cancer-survival gene products: survivin, Mcl-1, XIAP and/or cIAP2. While both studies tested the agent’s effectiveness against models of head-and-neck and colon tumors, other research from Dr. Li’s lab suggests that mesothelioma, ovarian and pancreatic cancers, and potentially other solid tumors, may also be good targets for treatment with FL118.

“This work represents a significant move forward,” notes Dr. Li, senior author on the study. “We’re targeting four of the most resilient and pervasive cancer survival mechanisms, and because the findings from preclinical testing have been so striking, we’re anxious to see FL118 tested in the clinical setting.”

Xiang Ling, MD, PhD, a senior scientist in RPCI’s Department of Pharmacology & Therapeutics, is co-author of the paper, “An intravenous (i.v.) route-compatible formulation of FL118, a survivin, Mcl-1, XIAP, and cIAP2 selective inhibitor, improves FL118 antitumor efficacy and therapeutic index (TI).” The study was e-published today and is available at http://goo.gl/y0oZy.

The work was supported in part by grants from the U.S. Department of Defense (PC110408), Mesothelioma Applied Research Foundation and Roswell Park Alliance Foundation, and by shared resources supported by the National Cancer Institute’s Cancer Center Support Grant to RPCI (P30CA016056).

Annie Deck-Miller, RPCI Senior Media Relations Manager; annie.deck-miller@roswellpark.org; 716.845.859

April = Donate Life Month

April 1, 2013 by BNMCin Campus-wide, Community, Homepage, Member Institution(s)1 Comment

Unyts kicks off April, Donate Life Month, with a schedule of events to bring awareness to the importance of organ, eye and tissue donations.

On Friday, April 5, at 9, 9:30 and 10 p.m., Niagara Falls will light up in green to show support for the efforts that will come this month, helping to bring about more awareness.
On April 6, the Peace Bridge will commemorate Donate Life Month by exuding green and blue lights on the bridge.
In its second year, the Bucket List Bash will commence at Statler City on April 12. Much like The Bucket List movie, the event will celebrate life, the ambitions and goals yet to be accomplished, offering many the opportunity to enjoy an evening doing what they have always dreamed of. Learn more about these events here.
To show your Unyts pride, on April 19, dress in your most outrageous blue and green. As an alternative to dressing in blue and green, you and your colleagues can decorate your company’s office space. When you share your blue and green photos on the Unyts Facebook page, you can be entered for a chance to win a signed Hodgson Sabres jersey.

Every person registered as a donor has the opportunity to help save a life. Regardless of age, race, or medical history, anyone can become a donor. Every organ and tissue donation goes to the person with the most need, no matter their socio-economic status. With more than 115,000 people on the national waiting list to receive organ, eye and tissue transplants that may either enhance or save their lives, the call to register is important. The response, though, is what will make a difference. Unfortunately, with more than 300,000,000 million people living in the United States, the need for donors is still greater than the supply.

According to Unyts, nearly 800 people in Western New York are waiting for lifesaving organs. Every 10 minutes, 1 person is added to the national transplant list. Visit the Donate Life Registry website and become a donor today. During the month of April, each presenting donor can receive a FREE 6-inch or Flatbread Breakfast Sandwich from any Subway in Buffalo. For more information, click here.

You can help give the gift of life.

Olmsted Center for Sight Names New President and CEO

March 28, 2013 by BNMCin Homepage, Member Institution(s), News2 Comments

The Olmsted Center for Sight Board of Directors elected Tammy Owen as the organization’s new president and chief executive officer.
Olmsted’s search committee underwent a national search for the successor of former president and chief executive officer, Ron Maier, after he retired in September 2012. There were 50 candidates being considered for the position. The seven-member search committee was able to narrow it down to three finalists. With over 20 years of experience working in health care operations, Owen was considered to be a great fit for the position.

Patricia Clabeaux, chairperson of Olmsted Center’s Board of Directors stated that “[Owen’s] strong background in health care management, with a special focus on service delivery, and a team-oriented, results-driven leadership style will serve us well.”

Throughout her 22 year tenure, Owen has held many leadership positions including vice president, ambulatory and rehabilitation services; vice president, strategic planning and network development; vice president, physician services; president, DeGraff Memorial Hospital; and president, Millard Fillmore Gates Hospital. In her most recent position, Owen served as the chief operating officer of the Buffalo General Medical Center/Gates Vascular Institute.

A Boston native, Owen received her Bachelor of Science degree in physical education/athletic training and her Master of Science degree in sports medicine/education from Springfield College in Springfield, Massachusetts. She went on to receive both her Bachelor of Science degree in physical therapy, and her MBA from the University at Buffalo.

She serves on numerous boards, has taught as an adjunct faculty member at both the University at Buffalo and Daemen College, and has been named in Buffalo Business First’s 2012 Top 50 Healthcare Executives and Women of Influence lists.

Owen will begin her tenure in April 2013, continuing the innovative provision of services for blind, visually impaired and physically disabled Western New Yorkers.

First Niagara Gives UB Land for Medical School

March 28, 2013 by BNMCin Allentown, Campus-wide, Construction, Member Institution(s), News

UB Acquires the Last of 3 Properties to Move Forward with Medical School Construction

First Niagara Financial Group Inc. has given the University at Buffalo (UB) a .85 acre of land to be incorporated into the UB School of Medicine and Biomedical Sciences site. The parcel of land at 973 Main Street is where a current First Niagara bank branch is located.

Although the land is considered a donation, in exchange for $1 First Niagara offered the land, worth wp-contentroximately $2 million, to assist UB in its quest to acquire the third property necessary for the building of the medical school.

Recognizing the importance of the land in UB's plan for the medical school, First Niagara's interim president and chief executive officer, Gary Crosby, stated that “We are committed to doing great things in our community and we are proud to collaborate with UB in order to provide the final piece of the puzzle for the new medical school to move forward.” He also stated that First Niagara is highly supportive of the region's efforts to continue being a recognized leader in life sciences, innovation and research.

Satish K. Tripathi, UB's president, said that “With [this most recent] acquisition, UB can move ahead with its plans for the new medical school, which will help to dramatically improve health care and medical education in our region while providing a significant boost to the local economy.”

The $375 million, 520,000-square-foot medical school will be located on the corner at Main and High Streets.

With high expectations to improve health care throughout Western New York and to attract patients from other areas, the move of the medical school will also contribute to the growing world-class Medical Campus and its vision to attract the best and the brightest. The medical school will be able to graduate more physicians who will most likely stay and practice in the area. Medical school students will have the opportunity to receive a great and invaluable educational experience while near facilities like the John R. Oishei Children’s Hospital, Buffalo General Medical Center, Gates Vascular Institute, Roswell Park Cancer Institute, the UB Clinical and Translational Research Center and others.

“UB will attract the most promising medical students and world-class faculty,” said Michael E. Cain, MD, UB vice president for health sciences and dean of the medical school. “The prospect of a brand new, 21^st century medical school next to teaching hospitals and state-of-the-art research laboratories in downtown Buffalo is helping UB to recruit top physicians and scientists, some of whom are already here.”

UB will add several new clinical service areas within the new medical school, providing specialty care and health services not currently offered in the region. Faculty will pursue cutting-edge research and collaborations with member institutions will lead to advanced care for patients.

On October 1st, First Niagara will relinquish the property to UB, later opening a new branch on the BNMC. Until the new branch opens, a temporary branch will be located at 1031 Main Street.

The groundbreaking for the new building is set for September and construction is expected to be completed in 2016.

*Design rendering by HOK , a global design, architecture, engineering and planning firm.

Read more about the this announcement below:

First Niagara Donating Downtown Land for UB Medical School

Land Donation Leads to First Niagara Branch Shuffle

First Niagara Provides Land for New UB Medical School Project

First Niagara Donates Land for New UB Med School

First Niagara Giving UB Main Street Land for $1

UB RIA Awarded Grant to Develop Telephone-based Clinical Skill Assessment Tool

March 22, 2013 by BNMCin Homepage, Member Institution(s), News2 Comments

Can alcohol and drug abuse clinician skills be assessed over the phone?

There is a growing trend to make clinical training available to alcohol and drug abuse treatment professionals via the Internet and through distance learning. It is cost effective and can deliver training in current evidence-based practices to audiences for whom access may be limited.

While ensuring that trainees can correctly wp-contently the clinical skills taught during training is crucial, evaluation of whether or not clinical skills are correctly wp-contentlied can be challenging because it is typically done through role playing. The assessment of role playing requires feedback as well as reviewing the wp-contentlication of that feedback.

When training is delivered via the Internet and/or through distance learning, clinical skills wp-contentlication assessment might require tools such as video conferencing, which are cost-prohibitive for many organizations.

The University at Buffalo Research Institute on Addictions (RIA) has been awarded a $267,469 National Institute on Alcohol Abuse and Alcoholism (NIAAA) grant to refine a telephone-based clinical assessment tool for evaluating the training of drug and alcohol counselors – a tool that is built on existing data – and then to conduct a psychometric evaluation for its effectiveness.

“The idea for the grant came about because of a challenge we encountered on a previous study — the ‘Behavioral Interventions with Couples Project’ or BIC project,” said Christopher Barrick, PhD, RIA research scientist and the principal investigator on the new grant.

According to Barrick, the previous study involved expert clinicians in the field of substance abuse who were trained in behavioral couples therapy. The research compared the effects of being trained at an in-person workshop versus distance learning via video conference. The objective was to assess gains in knowledge and clinical skill following the workshop. Assessing knowledge was straightforward – trainees were asked to respond to a web-based questionnaire.

“Assessing clinical skill was more complicated,” said Barrick.

“How could we conduct a role play, a traditional method of clinical skill assessment, with our distance-learning trainees, many of whom were in the greater Rochester area? Sending research staff to conduct in-person role plays would have been too time-consuming and costly.

“To address this need, we developed a method that used interactive voice recording (IVR). Essentially, trainees telephoned in and the IVR system acted like a sophisticated voice mail system, capturing unrehearsed responses to clinical questions. It was a good start, but the method needs refinement. That’s the goal of this current research grant.”

Barrick says the specific goals of the project are to refine and extend the existing assessment tool developed in the BIC project, and conduct a psychometric evaluation to examine the generalizability, alternate form reliability and construct validity of the tool.

“My co-investigator at RIA, Dr. Neil McGillicuddy, also a research scientist at the UB Research Institute on Addictions, has had experience developing similar instruments before, and I’m excited to collaborate with him on this project,” said Barrick.

Barrick says this particular project focuses on developing a methodology that could be used in a variety of fields.

“It just hwp-contentens that there is a trend toward making trainings available to substance abuse treatment clinicians via the Internet and other distance learning methods, so this is a good fit with the broader needs of the field at the moment.

“There is a lot of great treatment and intervention research currently going on in the substance abuse field. Unfortunately, there has been an ongoing problem of transferring that work into community practice. This project is a part of this broad area of research that looks at better ways to make the big investment in treatment and intervention research pay off and gets those results into the hands of people who can use it,” he said.

The grant is scheduled to run from December 2012 to December 2014.

Sara R. Saldi (UB); saldi@buffalo.edu; 716.645.4593

John R. Oishei Children’s Hospital Mock-Up Rooms Revealed

March 21, 2013 by BNMCin Construction, Health care, Homepage, Member Institution(s), News3 Comments

Seven new mock-up rooms were revealed during a tour inviting the media to view how rooms within the John R. Oishei Children’s Hospital may look.
The mock-up rooms shown have walls erected, and some include installed equipment. The rooms presented were the neonatal intensive care unit; pediatric intensive care unit; pre/post operative room; labor and delivery room; an ED urgent care room; medical/surgical/mother-baby room; and an operating room.

Design for the rooms is physician-, nurse-, clinical and support staff-, patient- and family member-inspired. A part of 27 user-groups total, those who provided feedback had it incorporated into the initial mock-up designs in order to meet the needs of its primary users and to provide the best possible care. Additional feedback from the user-groups regarding the mock-ups will help to determine design suggestions to consider. The groups have signed-off in agreement with the interior design and floor plans for the new hospital, completing the design and development phase of planning. The Physician-led Steering Committee and user-groups will move forward with the development of new process flows for patient care and other hospital operations for the Children’s Hospital, and the ambulatory care center to be housed within Ciminelli Real Estate’s medical office building, Conventus.

Spacious and more aesthetically pleasing, the hospital’s room infrastructure is being designed to accommodate new technology as well. In addition to being able to offer input, the groups get to use the newly constructed rooms to help develop new processes to deliver care within them. The goal for the hospital is for it to be recognized as the most innovative, highest quality, highest value provider and partner, and the regional referral center for women and children’s care for Kaleida Health in Western New York and beyond.

View a live webcam image of the construction site for the new John R. Oishei Children’s Hospital and Conventus, which will be connected by bridges on the second and third floors to the new hospital. It is expected to open in 2016.

(Top Right Photo – Dr. Teresa Quattrin, Pediatrician-in-Chief at Women & Children’s Hospital of Buffalo and UB Distinguished Professor, A. Conger Goodyear Professor and Chair of the Department of Pediatrics at the State University of New York at Buffalo, and Allegra Jaros, Vice President and Chief Operating Officer at Women & Children’s Hospital of Buffalo provides an update on plans for the John R. Oishei Children’s Hospital.)

More UB Medical School Students Choose Buffalo for Their Residencies

March 20, 2013 by BNMCin Homepage, Member Institution(s)

Fifty percent more students in the University at Buffalo School of Medicine and Biomedical Sciences have chosen a UB residency program this year than last year, according to statistics compiled on the graduates at Match Day 2013 held March 15.
Match Day is the day when medical school students around the country find out where they will do their postgraduate training, called a residency, which lasts from three to seven years, depending on the specialty chosen.

Thirty-eight out of the 150 students who make up the Class of 2013 have chosen to stay in Buffalo and do their residencies at UB, up from 24 in 2012, according to Roseanne C. Berger, MD, senior associate dean for graduate medical education.

“This is a vote of confidence in UB’s residency programs,” says Berger. “We do know that the residents have a tendency to remain in the areas where they train, so many will start their careers here, providing quality health care for our region.”

“We’re excited to see this,” agrees David A. Milling, MD, senior associate dean for student and academic affairs in the UB medical school. “We have recruited so many new faculty and the quality of our training programs continues to improve, so students are more receptive, not only staying in Buffalo for postgraduate training, but some who leave also will return once their training is complete. The growth of the Buffalo Niagara Medical campus, including the forthcoming medical school downtown, is also attracting young physicians here.”

Seventy-three percent of the UB Class of 2013 are New York State residents. A total of 75 students, half of the class of 2013, will stay in New York State to do their training.

Ellen Goldbaum (UB); goldbaum@buffalo.edu; 716.645.4605

Buffalo-Based Team Develops, Tests First Simulation-Based Robotic Surgery Training Curriculum

March 12, 2013 by BNMCin Homepage, Member Institution(s), News

Study results indicate Fundamental Skills of Robotic Surgery wp-contentears to be effective way to train surgeons

Researchers from Roswell Park Cancer Institute (RPCI) and four collaborating institutions have evaluated the effectiveness of a novel curriculum to safely train surgeons on the da Vinci Surgical System, which is used to perform robot-assisted surgeries. Results, published in Urology, showed that participants trained in the curriculum executed key skills with greater precision than those who did not receive training.

The Fundamental Skills of Robotic Surgery (FSRS) training curriculum, jointly developed by the study authors, uses the Robotic Surgical Simulator (RoSS) to train surgeons in four basic areas required in robot-assisted surgeries: orientation, motor skills, basic surgical skills and intermediate surgical skills. Launched in 2010, RoSS, one of the first robotic surgical simulators to accurately simulate the da Vinci system, was developed by Khurshid A. Guru, MD, director of robotic surgery at RPCI, and Thenkurussi Kesavadas, PhD, director of the Virtual Reality Lab and a professor of mechanical and aerospace engineering at the University at Buffalo (UB).

In this study, the researchers recruited 53 surgeons, fellows, residents and medical students from four institutions: RPCI, UB, the Henry Ford Health System (HFHS) in Detroit, Mich., and the Cleveland Clinic (CC) in Cleveland, Ohio. Most of the participants had no prior robotic or laparoscopic surgical experience. The researchers randomly divided them into control and experimental groups. Participants in the experimental group completed the four-hour FSRS course; those in the control group did not.

On a series of three tests, participants in the experimental group executed a series of three tasks with more precision than their counterparts who did not complete the FSRS curriculum, and completed the tasks more quickly overall. Moreover, average performance improved considerably for 23 “crossover” participants who did not receive the initial training but were allowed to repeat the three tests following FSRS instruction.

It’s critically important that institutions that offer robot-assisted surgeries develop training programs for their surgeons that realistically simulate the surgical environment and build user proficiency in core skills, notes Guru, senior study author.

“A situation where surgeons train only in the O.R., on live patients, is far from ideal,” he says. “The importance of this study is that it gives us the first evidence we have that a carefully designed, structured training curriculum carried out in a risk-free, simulated environment is an effective way to translate the basic skills required in robot-assisted surgery. The implications for improvements in patient safety and long-term outcomes are tremendously encouraging.”

“The idea of a simulation-based curriculum is gaining widespread acceptance, and FSRS is now being used in many leading robotic-surgery training programs nationally and internationally,” adds Kesavadas, a co-author on the study and co-developer of the RoSS simulator.

“This study shows the value of a structured curriculum while exposing a laparoscopically naive surgeon to the robotic platform,” says Mani Menon, MD, the Raj and Padma Vattikuti Distinguished Chair and Director of the Vattikuti Urology Institute at HFHS. “Given the enormous cost of health care, any effort at off-line training is of tremendous value.”

The researchers plan to do further research to establish the extent to which completion of the FSRS curriculum may impact long-term surgical proficiency. The development, testing and validation of RoSS and the FSRS curriculum were facilitated by donations to the Roswell Park Alliance Foundation and support from the John R. Oishei Foundation.

“The John R. Oishei Foundation is committed to supporting projects that will enhance patient safety and quality of care in Western New York and beyond,” says Robert D. Gioia, Oishei Foundation President. “We’re pleased to support the research around the FSRS curriculum, which has been shown to enhance the training of robotic surgeons in a structured and safe environment.”

The study, “Fundamental Skills of Robotic Surgery (FSRS): A multi-institutional randomized controlled trial for validation of a simulation-based curriculum,” can be accessed at http://goo.gl/hqck8.

Additional co-authors are Andrew Stegemann, Johar R. Syed, Shabnam Rehman, Gregory E. Wilding, Mohamed Sharif, Amrith Rao and Yi Shi, for RPCI; James M. Hassett and Ashirwad Chowriwp-contenta of UB; Khurshid Ghani and James O. Peabody of HFHS; Riccardo Autorino and Jihad Kaouk of CC; and Kamran Ahmed of MRC Centre, Guy’s Hospital, Kings College, London, United Kingdom.

Cory Nealon (UB); cmnealon@buffalo.edu; 716.645.4614
Annie Deck-Miller, RPCI Senior Media Relations Manager; annie.deck-miller@roswellpark.org; 716.845.859

SSO 2013 Lineup Includes 5 Talks by Roswell Park Cancer Institute Physicians

March 11, 2013 by BNMCin Homepage, Member Institution(s), News

Presentations by RPCI surgeons cover issues of biomarker identification, quality improvement, treatment decisions

Five Roswell Park Cancer Institute (RPCI) physicians were invited to give oral presentations on cancer research March 8 at the 66th annual Cancer Symposium of the Society of Surgical Oncology, an international society for cancer surgeons. They were among 10 RPCI physicians who presented at this year’s meeting in National Harbor, MD. The symposium is a major annual meeting where new advances in cancer care are presented.

John M. Kane III, MD, FACS, Chief of the Melanoma/Sarcoma Service within the Department of Surgical Oncology, is first author on “High Risk Soft Tissue Sarcoma Biomarker Expression Patterns and Outcome Following Neoadjuvant Chemoradiation” (abstract 64; session: Sarcoma). Dr. Kane, a member of the Radiation Therapy Oncology Group (RTOG) sarcoma working group, presented research performed through his RTOG Translational Research Program grant from the National Cancer Institute.

Because outcomes for patients with “high-risk” soft-tissue sarcoma (STS) — those tumors that are large, deep and high-grade — are often poor, high priority has been placed on identifying biomarkers that might predict response to therapy and survival. Dr. Kane and a multi-institutional team of collaborators created tissue microarrays using pre- and post-treatment STS tumor samples from participants from two clinical research studies, looking to see how treatment impacted levels of seven different biomarkers. They found that two biomarkers, CAIX (carbonic anhydrase IX) and GLUT 1 (glucose transporter 1), decreased following neoadjuvant chemoradiation. The researchers also found that increased post-treatment p53 expression correlated with a higher chance of cancer recurrence.

“We’re always looking for ways to determine which patients might truly benefit from chemotherapy, sparing other patients that do not need it the potential side effects,” notes Dr. Kane. “In addition, these microarrays can also be used to identify new targeted therapies for these often-deadly sarcomas.”

Co-authors are Qiang Zhang, PhD, Asha George, MS, and William Kraybill, MD, of Radiation Therapy Oncology Group, Philadelphia, PA; Thomas DeLaney, MD, of Massachusetts General Hospital, Boston, MA; Alex Klimowicz, PhD, of the Tom Baker Cancer Centre, Calgary, Alberta, Canada; Anthony Magliocco, MD, of the Moffitt Cancer Center, Tampa, FL; and Jeff Simko, MD, PhD, of the University of California, San Francisco, San Francisco, CA.

Shicha Kumar, MD, an Assistant Professor in the Department of Surgical Oncology, is first author on “Clinical Impact of Real Time Reporting Using the Commission on Cancer’s Rapid Quality Reporting System: Is It Worthwhile?” (abstract 55; session: Quality Improvement/Clinical Outcomes).

Quality-control measures have been shown to correlate with improved cancer outcomes, yet deviations from desired standards of care often go undetected or are discovered late, limiting or preventing opportunities for effective intervention. The research team set out to assess the clinical impact of the Rapid Quality Reporting System (RQRS), a tool developed by the Commission on Cancer for alerting providers to wp-contentroaching deviations from predetermined quality measures. They found that while relatively few deviations from standards occurred, RQRS is an easy-to-use tool for proactively identifying and improving delivery and documentation of cancer care.

“Our analysis shows the Rapid Quality Reporting System to be a helpful and reliable safety mechanism for identifying patients at risk for lapses in wp-contentropriate care,” Dr. Kumar says. “The providers we surveyed indicated that the system spurred more effective teamwork and improved documentation, and resulted in reduced concern over insufficient or delayed follow-through.”

Co-authors are Marian Betrus, Jaemi Fitzgerald, Camille Rinaldo, Kassia Delgado, Linda Hauck and Stephen Edge, MD, all of RPCI.

Moshim Kukar, MD, a clinical fellow in the Department of Surgical Oncology, is first author on “Fostering Coordinated Survivorship Care in Breast Cancer: Who is ‘Lost to Follow-Up’?” (abstract 57; session: Quality Improvement/Clinical Outcomes).

Patients who stop scheduling or showing up for wp-contentointments are a concern for many oncology providers. They are considered “lost to follow-up” (LTFU) when they stop seeking services or ongoing monitoring from a facility without having a transfer-of-care plan in place. Dr. Kukar and colleagues looked at nearly 13 years of RPCI records for patients treated for breast cancer, classifying them as LTFU if they had a two-year gap in visits to the facility. They then looked at patient, tumor and treatment characteristics to see whether any particular factors were correlated with LTFU status. They identified five characteristics associated with increased incidence of care abandonment: older age, earlier-stage disease, living longer distances from the facility, having no need for additional adjuvant therapies and absence of recurrence.

“We know that many breast cancer patients will self-triage away from oncology care and follow-up,” says Dr. Kukar. “This research shows that we have a real opportunity to prospectively identify who these women are so we can better assist them with the transfer of care to other providers and make sure that continuity of care is maintained.”

Co-authors are Nancy Watroba, MPA, Austin Miller, PhD, Dr. Kumar and Dr. Edge, all of RPCI.

Jacqueline Oxenberg, MD, a clinical fellow in the Department of Surgical Oncology, is first author on “Neoadjuvant Chemotherapy to Define Biologic Behavior Prior to Resection of Primary Angiosarcoma” (abstract 71; session: Sarcoma).

In a retrospective review of RPCI patients treated for angiosarcoma, a rare and biologically aggressive tumor, the research team tested their hypothesis that neoadjuvant chemotherapy would provide insights that could help guide treatment decisions, particularly by defining those who would not benefit from more involved, higher-risk surgeries. They found that chemotherapy administered preoperatively was well tolerated and significantly decreased tumor size, decreased the number of surgeries needed to control tumors and was not associated with any increase in complications.

“We now have evidence that giving chemotherapy prior to surgical removal of angiosarcoma tumors allows us to better identify which patients would benefit most from surgery,” Dr. Oxenberg explains. “It’s an wp-contentroach that wp-contentears to be both effective and easy to implement.”

Co-authors are Dr. Kane, Nikhil Khushalani, MD, Kilian Salerno May, MD, and Kristopher Attwood, PhD, all of RPCI.

Timothy Platz, MD, is first author on “The Use of Modified 4-Dimensional Computed Tomography in 100 Consecutive Patients with Primary Hyperparathyroidism: An Argument for the Abandonment of Sestamibi SPECT” (abstract 25; session: Endocrine Cancer).

For many years, the vast majority of providers performing parathyroidectomy have used ultrasound and/or Sestamibi SPECT imaging technologies to help identify abnormalities and guide surgical planning. Looking at patients treated at RPCI between December 2010 and July 2012, Dr. Platz and colleagues performed a comparative analysis to determine whether a newer imaging option, 4-Dimensional Computed Tomography (4D-CT), might be an effective alternative to those standard imaging technologies. The team found that a modified form of 4D-CT, adapted to include volume rendering highlights the parathyroid abnormality in relation to neighboring structures, was superior to sestamibi SPECT and ultrasound, with similar levels of radiation exposure.

“We found that this modified 4D-CT wp-contentroach was much more reliable than the other modalities in providing a preview of the anatomy that we’d encounter when actually performing the surgeries,” notes Dr. Platz. “The distinctions between these wp-contentroaches proved to be so significant that we can present a persuasive case for other providers to consider abandoning sestamibi SPECT for these types of cases.”

Co-authors are Ahmed Abdelhalim, MD, Adrienne Groman and William Cance, MD, all of RPCI.

Annie Deck-Miller, RPCI Senior Media Relations Manager; annie.deck-miller@roswellpark.org; 716-845-8593

New Biotech Companies Move Into Innovation Center on the Buffalo Niagara Medical Campus

March 11, 2013 by BNMCin Biotechnology Companies, Healthy Communities, Homepage, Innovation Center, Member Institution(s), News

The Thomas R. Beecher, Jr. Innovation Center is pleased to welcome Roswell Park Cancer Institute (RPCI) spin-off companies Tartis Aging, Inc., and OncoTartis, Inc., as its newest tenants. The companies will occupy a combined 5,700-square-foot of wet lab and office space on the fourth floor of the building. Approximately half of this space will be built up as the companies continue to grow in size.
OncoTartis and Tartis Aging are discovery-stage biotechnology companies seeking novel anti-cancer and anti-aging drugs. Their proprietary technologies are licensed from the laboratories of Andrei Gudkov, PhD, from RPCI.

Dr. Gudkov was recruited to Buffalo by RPCI and other local partners in 2007. He moved his research lab and his first commercial company, Cleveland BioLabs, Inc. (CBLI), from the Cleveland Clinic to serve as Senior Vice President of Basic Science and Chair of the Department of Cell Stress Biology at Roswell Park.

The laboratory building at 73 High Street, shared with Cleveland BioLabs, Inc., had been the first home for both corporations. With 15 employees and a growing portfolio, the two companies have outgrown the space available on High Street but wanted to remain on the BNMC.

“We are very hwp-contenty to find space in the Innovation Center, which allows us to expand our research and at the same time continue to be close to our colleagues at CBLI and Roswell Park,” said Aleksandra Kotlyarova, Director of Operations for both companies.

“OncoTartis and Tartis Aging are perfect examples of what we need to see more of here in Buffalo,” said Patrick J. Whalen, Chief Operating Officer of the BNMC, Inc., which owns and operates the Innovation Center. “Dr. Gudkov and Cleveland BioLabs moved to the BNMC several years ago to better collaborate with Roswell Park Cancer Institute, and thanks to the groundbreaking research at Roswell Park, they continue to grow and spin off companies, creating more jobs and economic-development opportunities in Buffalo as they evolve.”

Kari Bonaro (BNMC, Inc.); kbonaro@bnmc-old.local; 716.218.7157

New Biotech Companies Move Into Innovation Center on the Buffalo Niagara Medical Campus

March 11, 2013 by BNMCin Campus-wide, Innovation Center, News, Research

FOR IMMEDIATE RELEASE
Monday, March 11, 2013

For more information, contact:

Contact Kari Bonaro
kbonaro@bnmc-old.local, 716.218.7157

(BUFFALO, NY) – The Thomas R. Beecher, Jr. Innovation Center is pleased to welcome Roswell Park Cancer Institute (RPCI) spin-off companies Tartis Aging, Inc., and OncoTartis, Inc., as its newest tenants. The companies will occupy a combined 5,700 sq. ft. of wet lab and office space on the fourth floor of the building. Approximately half of this space will be built up as the companies continue to grow in size.

OncoTartis and Tartis Aging are discovery-stage biotechnology companies seeking novel anti-cancer and anti-aging drugs. Their proprietary technologies are licensed from the laboratories of Andrei Gudkov, PhD, from RPCI.

About the Buffalo Niagara Medical Campus

The Buffalo Niagara Medical Campus (BNMC) is dedicated to the cultivation of a world-class medical campus for clinical care, research, education, and entrepreneurship on 120 acres in downtown Buffalo. It is home to the region’s top clinical, research, and medical education institutions, including: the University at Buffalo, Roswell Park Cancer Institute, Olmsted Center for Sight, Kaleida Health, Hauptman-Woodward Medical Research Institute, Buffalo Medical Group, Buffalo Hearing & Speech Center, Unyts, and the Center for Hospice and Palliative Care. There are over 40 public and private companies on the BNMC. More than 12,000 people come to work at the Medical Campus every day, and BNMC institutions see over one million patients and visitors annually. The Campus has an annual economic impact of $1.5 billion on the region. The Medical Campus consists of more than 6 million square feet of research, clinical, and support space. bnmc-old.local

About Roswell Park Cancer Institute

The mission of Roswell Park Cancer Institute (RPCI) is to understand, prevent and cure cancer. RPCI, founded in 1898, was one of the first cancer centers in the country to be named a National Cancer Institute-designated comprehensive cancer center and remains the only facility with this designation in Upstate New York. The Institute is a member of the prestigious National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers; maintains affiliate sites; and is a partner in national and international collaborative programs. For more information, visit RPCI’s website at http://www.roswellpark.org, call 1-877-ASK-RPCI (1-877-275-7724) or email askrpci@roswellpark.org.

About the Thomas R. Beecher Innovation Center

The Thomas R. Beecher, Jr. Innovation Center, located at 640 Ellicott Street in downtown Buffalo, is a LEED-certified research and development space housing life sciences and biotech companies, as well as companies offering support services like IP attorneys, talent acquisition, sales, and marketing. This state-of-the art facility is designed to accommodate small to medium companies seeking office, wet lab and/or research space, on a month-to-month basis or via longer term leases, located in the heart of the thriving Buffalo Niagara Medical Campus. There are currently 40 companies located in the building.

The Innovation Center is owned and operated by the BNMC, Inc., a not-for-profit organization that fosters conversation and collaboration among its member institutions, their 12,000 employees, and the community; coordinates activities related to sustainable planning, development and enhancement of its 120-acre space; and works to create a distinct, innovative environment that provides opportunities for entrepreneurship and active and healthy living.

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Brain Imaging to Identify Physical Reasons Why IBS Symptoms Improve with Drug-free Treatments

March 7, 2013 by BNMCin Health care, Homepage, Member Institution(s), News, Research4 Comments

UB researchers and colleagues will correlate objective measures of brain changes with patients’ reports of relief from symptoms of irritable bowel syndrome

Patients who suffer from the painful, often disabling, symptoms of irritable bowel syndrome (IBS) often are surprised to find that behavioral changes, not drugs, provide significant relief.

Now, researchers at the University at Buffalo who have pioneered some of these behavioral treatments, along with colleagues at the University of California, Los Angeles, and Northwestern University, are using functional and structural magnetic resonance imaging (MRI) to reveal the biological basis for the relief. The research could help doctors choose the best treatment method for individual patients and could improve the quality of life for millions of people with IBS.

“We’re going to look at biological mechanisms that underlie these non-drug treatments, to discover what is going on in the brain that explains treatment benefits achieved by teaching patients specific skills to control and reduce their symptoms,” says Jeffrey M. Lackner, PhD, associate professor of medicine at the UB School of Medicine and Biomedical Sciences and a project principal investigator. “By using a brain scan to compare brain activity before and after treatment, we expect to get a picture of changes in the brain that correspond to improvements in gastrointestinal symptoms.”

The work is funded by a $2.3 million grant to UCLA, the lead institution; Northwestern; and UB by the National Institute of Diabetes and Digestive and Kidney Diseases. It builds on the work of UCLA researchers at its Oppenheimer Family Center for Neurobiology of Stress and a pilot neuroimaging study conducted by Lackner and colleagues at UB.

The brain imaging study came about partly as a result of a major, $8.9 million, seven-year, multi-site clinical trial Lackner is leading at UB to test behavioral treatments in IBS patients. It is the largest IBS clinical trial conducted to date and one of the largest behavioral trials ever funded by the NIH without a drug component. Developed at UB, these treatments are regarded as some of the most powerful treatments available to IBS sufferers.

Lackner is currently recruiting IBS patients for the behavioral and imaging studies at the Behavioral Medicine Clinic of the UB Department of Medicine at Erie County Medical Center. For more information on participating in one of the studies, call 716-898-4458 and leave a name, telephone number and convenient times to be contacted.

IBS is among the most common, disabling and intractable gastrointestinal disorders. Twice as common among women as men, it is estimated to affect between 25 million and 50 million Americans. Symptoms include pain, stomach cramps, bloating, diarrhea and/or constipation.

“We’re excited about the possibility of providing the first evidence for biological markers that correlate with treatment-induced symptom changes, and developing a better understanding of the mechanism behind IBS,” says Lackner. “Such cutting-edge translational research is going to help foster individualized, specific treatments for patients.”

One treatment developed at UB aims to control symptoms by changing specific thinking patterns and behaviors found to aggravate IBS. Using state-of-the-art brain-imaging methods, UCLA researchers, under the leadership of Emeran Mayer, MD, hope to identify the biological mechanisms underlying their effectiveness. Mayer is a professor of medicine and psychiatry at UCLA, director of the Oppenheimer Center for Neurobiology of Stress and principal investigator of the imaging study.

Scientists believe that IBS symptoms are the result of dysregulation of brain-gut interactions, resulting in abnormal muscle contractions in the gut and heightened sensitivity to painful stimuli.

“Just as faulty wiring between the neural connection of the brain and gut can bring on symptoms, so learning new ways of thinking and behaving may ‘rewire’ brain-gut interactions, resulting in reduced pain and bowel symptoms that otherwise take a major toll on patients,” says Lackner. “Determining whether behavioral treatments work by targeting specific areas of the brain that have a direct effect on gut function and sensation is a major goal of this study.”

Correlating structural brain changes with symptom reduction is, for both Lackner and Mayer, a primary goal that they say will demonstrate an ‘organic’ component to IBS, which is critical. “IBS is often unfairly dismissed as a psychosomatic condition,” says Mayer. “These findings will be important in dispelling the notion once and for all that IBS symptoms are not real and are ‘only psychological.’”

Lackner’s UB’s colleagues on the study include Michael Sitrin, MD, professor, Christopher Radziwon, PhD, research assistant professor, Greg Gudleski, PhD, clinical research assistant professor, Leonard Katz, MD, professor emeritus and Rebecca Firth, senior research support specialist, all in the Department of Medicine and Susan Krasner, PhD, clinical assistant professor of anesthesiology.

Ellen Goldbaum (UB); goldbaum@buffalo.edu; 716.645.4605

BNMC Hosts GO Party to Highlight Alternative Ways for Employees to Get to Work

March 5, 2013 by BNMCin Campus-wide, Employees, Event, Healthy Communities, Transportation, WellnessLeave a Comment

FOR IMMEDIATE RELEASE
Tuesday, March 5, 2013

For more information, contact:

Kari Bonaro, Director of Communications
kbonaro@bnmc-old.local or 716.218.7157

MEDIA ALERT

BNMC Hosts GO Party to Highlight Alternative Ways for Employees to Get to Work

About 100 Employees Expected to Attend the Transportation-Themed Event Focusing on Smarter, Greener, Healthier Ways to Get to Work

WHAT: GO Party, a free hwp-contenty hour event for employees on the Buffalo Niagara Medical Campus (BNMC) who are members of GO BNMC. GO BNMC is a campus-wide movement to connect employees with healthier, greener, and affordable transportation options.

WHEN: Wednesday, March 6^th from 4-7pm

WHERE: Ulrich’s Tavern, 674 Ellicott Street

This free event ($5 for non-members) will highlight innovative and economical ways in which GO BNMC, a commuting and rewards initiative, aims to advance an innovative and sustainable transportation system that focuses on walking, bicycling, Metro Bus and Rail, and carpooling and vanpooling over drive-alone trips to and from the Medical Campus.

Employees will learn about the different transportation options available on the BNMC that can help them save money, get fit, and create a more sustainable environment, with the overall goal to improve employee’s abilities to get around in healthier, greener, and more economical ways.

GO BNMC is a campaign of the Buffalo Niagara Medical Campus, Inc. in partnership with NYSERDA & NYSDOT.

About the Buffalo Niagara Medical Campus, Inc.

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UB Goes to Great Lengths to Recruit Top Medical Talent to Buffalo – Buffalo News Story

March 4, 2013 by BNMCin Amenities, Attractions, Employees, Member Institution(s)6 Comments

(Photo from The Buffalo News)

Published: 03/3/2013, 11:54 PM Updated: 03/3/2013, 11:54 PM

Buffalo News Article: The Buffalo Niagara Medical Campus – and the opportunity for growth it promises – is helping UB attract some of the country’s top doctors to its medical school faculty.

BY: Jay Rey /Buffalo News Staff Reporter

Recruiting top doctors and medical researchers to Buffalo is not unlike the Bills or Sabres going after blue-chip free agents.

Buffalo may not be high on their list of destinations – or on their list at all – when bigger, warmer or more lucrative markets are out there.

Buffalo? thought Dr. Andrew Talal.

Dr. Gil Wolfe was hesitant, too.

And Dr. John Tomaszewski was sure Buffalo wasn’t for him, even before he stepped off the plane.

That’s part of the recruiting process the University at Buffalo is going through right now as it grows its School of Medicine and Biomedical Sciences.

Over the next three years, UB plans to hire more than 100 full-time medical faculty members in preparation for the 2016 opening of its new medical school, which will serve as a linchpin for an emerging Buffalo Niagara Medical Campus.

But luring smart, high-priced medical talent to the region isn’t as impossible as you might think.

If you can get them to visit – that’s the key – Buffalo can convince them it is a city on the rise and they can be a part of building something special.

“People want to be in a place that’s moving forward with a vision,” said UB President Satish Tripathi. “The way I feel is, if we are able to clearly state our vision and provide them the resources to succeed, people will come.”

“You got to get them on the airplane,” said Dr. Anne Curtis, chairwoman of the department of medicine at UB, who was recruited a few years ago. “Get them on the airplane and get them here, and then we can do OK.”

That’s why Talal, Wolfe and Tomaszewski eventually came around to Buffalo, with dozens more expected to follow.

“I began to understand that there really is a new day in town,” said Tomaszewski, who came from Philadelphia more than a year ago.

The added faculty will allow UB to increase enrollment at the medical school, from which the region gets many of its future physicians.

In addition, these newly hired doctors – who will set up practices and labs and hold positions at area hospitals – will bring some needed depth and breadth to Buffalo’s medical community, as UB targets specialists in areas where the region has a shortage.

It’s helping set the stage for a better, 21st-century health care system, where people from the region can be treated for most any condition by local doctors, said Michael Cain, vice president of health sciences and dean of the medical school.

And in a way, it serves as a reminder that Buffalo really is making progress, especially when the community’s Rust Belt image is seen through the fresh eyes of these newcomers.

“We fell in love with the city,” said Dr. Anthony Martinez, an associate professor of medicine, who moved to Buffalo from San Diego in December. “It just feels like there’s something going on here. It’s hard to describe, it’s just something you feel.”

But first, you have to get them to Buffalo.

Seeing the potential

Actually, Cain said, it hasn’t been that difficult.

“In all the recruiting I’ve done in the past six years, I’ve had no one turn us down because it was Buffalo,” Cain said.

In fact, UB landed its top choice for each of the 10 leadership positions recently filled for the medical school, Cain said.

They see the potential in Buffalo.

UB and Kaleida Health opened a state-of-the-art research building last year on Ellicott Street.

An 11-story addition to Roswell Park Cancer Institute breaks ground this year.

A new Women & Children’s Hospital is expected to open in 2016 – as is UB’s $375 million medical school.

“If you come here,” Cain tells the recruits, “you’re going to be part of a growing, expanding academic health center, and after four or five years, you will feel that you have contributed to making something better.”

It’s a vision that attracted Curtis, who came to UB in 2010 from the University of South Florida in Tampa, where she was chief of cardiology.

“People who are builders get excited about that,” Curtis said. “They see an opportunity to put their mark on something.”

Buffalo also caught the attention of Dr. Vanessa Barnabei, who had other offers but came to UB last fall from the Medical College of Wisconsin in Milwaukee, where she was director of obstetrics and gynecology.

“When I came here, I was very impressed by the opportunity for growth that’s going on, that’s being planned and is actually going to hwp-contenten,” Barnabei said. “You never know sometimes. People make these grand plans. But here, it really does look like it’s going to move forward.”

UB has been hiring for the medical school the past few years to fill vacancies and replace retired professors. Currently, the medical school has 720 full-time faculty members.

But the university wants to increase that number to as many as 850 over the next three years, as the need to train more physicians grows around the U.S.

A combination of resources – including philanthropy and money raised from state tuition increases – will be used to finance the school’s growth.

It’s that commitment of funds to build a better medical program at UB that helped lure Wolfe, who arrived at the end of 2011. He was recruited from the University of Texas Southwestern Medical School in Dallas to head the department of neurology at UB.

“This was not the first chair opportunity I was offered,” Wolfe said, “but looking back and hearing what hwp-contentened in those other situations, I’m glad I’m here. The level of state support – and even community support – doesn’t match what I’ve experienced here.”

That’s not to say the initial reaction to Buffalo is always enthusiastic.

Intriguing interview

Tomaszewski was recruited from the University of Pennsylvania in Philadelphia.

As he arrived in Buffalo for his first interview, the Philadelphia native remembers looking out the window of the plane and thinking: “I am not coming to Buffalo.”

But Tomaszewski’s interview was intriguing. It turned into another visit, then another. And during every conversation, another dimension he found engaging was revealed. He became chairman of the department of pathology and anatomical sciences at UB in the fall of 2011.

“Buffalo has a whole bunch of cards assembled to be a first-rate, modern health care system in the model that’s going to be successful going forward,” he said.

Talal, who was recruited from Weill Cornell Medical College in New York City, had a similar reaction when he received an email from the search firm.

“Who wants to go to Buffalo?” Talal thought to himself.

He promptly deleted the email.

But after being asked to speak in Buffalo, Talal learned more about what was going on at the university and the emerging medical campus. His opinion was changing.

When Talal returned to Manhattan, he reached out to the search firm. It took his daughter getting admitted to City Honors School and his wife – who is also a professor – to be recruited by UB, but Talal eventually joined the university in September as chief of the division of gastroenterology, hepatology and nutrition.

“Buffalo is an interesting community in the sense you have a lot of very top-notch things, but they haven’t been highly publicized,” Talal said. “There’s a lot more here than the city is given credit for.”

Now the recruited have become the recruiters.

A rare opportunity

The doctors acknowledge that Buffalo can be a tough market to recruit.

It’s just enough out of the way and close enough to major metropolitan areas, where top talent would rather head, Barnabei said.

But they also believe the medical growth planned for Buffalo is a rare opportunity for faculty, especially at a time when schools around the country are trying to cut costs.

“A lot of academic medical centers in 2013 are not growing,” Curtis said. “They see health care changing. They don’t see a need for more people. They’re treading water. Their staffs are full.”

“There are good people coming out of training who want an academic career but are finding the opportunities are somewhat [more] limited than in the past,” Curtis said.

“Times are tight,” added Tomaszewski. “California is a good example. Because of its finances, it really had to downsize its state university system, so there’s a lot of faculty on the market.”

And once the prospects see Buffalo, they understand the wp-contenteal.

“I enjoy Buffalo,” Wolfe said. “I’ve become a big booster for the city. I have to be, but I can do it in a sincere fashion. There are great recreational opportunities. The arts are excellent. The restaurant scene holds its own very well in comparison to even larger cities. And the cost of living, from a real-estate standpoint, is a big bonus.”

Barnabei and Tomaszewski were struck by the friendliness of the community. He recalled moving into his office – arms full, fumbling with his access card – when a woman saw him from the third floor of the building and came down to open the door for him.

“If you keep an open mind enough to give it a chance, it’s the kind of place that the more you look the more you find,” Martinez said. “If you just give it a chance, the more it gets under your skin and grabs you.”

When Talal, his former mentor, recruited Martinez to Buffalo from the University of California, San Diego, Martinez and his wife rented a place in Elmwood Village for a week to determine if Buffalo would suit them.

Martinez, a native of Providence, R.I., and a huge hockey fan, immediately got Buffalo. He saw how the cold weather and tough economy shaped this community for the good.

“I’ve never been in a place that has such a strong sense of community. That seeps into the people and permeates out,” Martinez said. “It’s a great fit for my family and a great fit for me.”

email: jrey@buffnews.com

Breakthrough Prize in Life Sciences Honors Researchers Making a Difference

February 28, 2013 by BNMCin Campus-wide, Homepage, Life Sciences Companies, News, Research3 Comments

A group of innovative and influential tycoons came together to form the Breakthrough Prize in Life Sciences, recognizing individuals who have made significant contributions in the life sciences field. The most lucrative prize offered for any academic achievement in the world, the first group to receive the annual Breakthrough Prize included 11 recipients, all scientists, in February. The awardees received $3 million and recognition for their “excellence in research aimed at curing intractable diseases and extending human life.”
Lauretes included:

Cornelia I. Bargmann – For the genetics of neural circuits and behavior, and synaptic guidepost molecules.
David Botstein – For linkage mwp-contenting of Mendelian disease in humans using DNA polymorphisms.
Lewis C. Cantley – For the discovery of PI 3-Kinase and its role in cancer metabolism.
Hans Clevers – For describing the role of Wnt signaling in tissue stem cells and cancer.
Napoleone Ferrara – For discoveries in the mechanisms of angiogenesis that led to therapies for cancer and eye diseases.
Titia de Lange – For research on telomeres, illuminating how they protect chromosome ends and their role in genome instability in cancer.
Eric S. Lander – For the discovery of general principles for identifying human disease genes, and enabling their wp-contentlication to medicine through the creation and analysis of genetic, physical and sequence maps of the human genome.
Charles L. Sawyers – For cancer genes and targeted therapy.
Bert Vogelstein – For cancer genomics and tumor suppressor genes.
Robert A. Weinberg – For characterization of human cancer genes.
Shinya Yamanaka – For induced pluripotent stem cells.

Russian venture capitalist and entrepreneur, Yuri Milner, established the prize along with additional founding sponsors Sergey Brin, Priscilla Chan, Anne Wojcicki and Mark Zuckerberg. All accomplished Internet and business gurus in their own right, the group has already guaranteed that the prize be presented for the next 5 years.

Life sciences companies including those involved with biotechnology, pharmaceuticals and biomedicine are coming up with innovative and effective ways to treat different types of cancer. Academic and health care institutions are leading research efforts to use genomics to identify personalized medicine. With all of the developments taking place on the Buffalo Niagara Medical Campus alone, it is easy to understand why it is important to recognize the individuals making life-enhancing discoveries. The Prize is public validation that the work being done in labs, under the microscopes, in the manufacturing companies and during simulations is highly valued and respected.

“I believe this new prize will shine a light on the extraordinary achievements of the outstanding minds in the field of life sciences, enhance medical innovation, and ultimately become a platform for recognizing future discoveries,” said Art Levinson. In addition to his current position as Chairman of both the Apple Inc. and Genentech Boards, Levinson will serve as the Chairman of the Board of the Breakthrough Prize Foundation.

Bound to spark an influx of submissions for consideration since any third party can nominate a researcher or scientist for the Prize, the major qualification is that it must recognize a major achievement, with special attention to recent developments. A person can win the Prize any number of times and there are no age requirements. The Prize can also be shared amongst a group of people.

In realizing that the next generations will lead the development of the next big breakthrough, the Prize is a recognition well-deserved for those whose jobs may not be as glamorous or well-known. It will serve as one more way to shed light on how impactful and relevant scientists and researchers are and will open the door for more students to take interest in pursuing those career paths.

International Partnership to Train and Educate Future Nanotechnologists in Zimbabwe

February 21, 2013 by BNMCin Homepage, Life Sciences Companies, Member Institution(s), Research5 Comments

The University at Buffalo (UB) welcomed Minister of Science and Technology Development of Zimbabwe, Professor Heneri Dzinotyiweyi to Buffalo to tour its Institute for Lasers, Photonics and Biophotonics (ILPB) and New York State Center of Excellence in Bioinformatics and Life Sciences (CoE). Both research facilities will play a role in the international academic partnership with the University of Zimbabwe and Chinhoyi University of Technology.
Receiving the award to establish a Fogarty International Center AIDS International Training and Research Program (AITRP) in 2009, UB professor, CoE associate director, and director of Translational Pharmacy Research Gene D. Morse, PharmD and collaborators set out to use the award for its intended purpose, providing education and training for HIV-related research in low- and middle-income countries.

Through the Zimbabwe International Nanotechnology Center (ZINC), the collaboration will primarily serve as a nanotechnology research program where UB will help educate and train young researchers at the University of Zimbabwe and the Chinhoyi University of Technology to wp-contently nanotechnology to treat and prevent prevalent diseases like HIV/AIDS, tuberculosis and malaria in the south-African country. Nanotechnology is molecular manufacturing on a 100 nanometer or smaller scale. Nano-particles (particles with dimensions less than 100 nanometers) have become important to the equation of new HIV/AIDS drug development because they can provide effective treatment options with shortened duration of therapy, reduced systemic side effects and limited development of drug resistance.

With 14 percent of Zimbabwe’s population living with HIV/AIDS and tuberculosis as a co-infection, the need for new drugs and new formulations of available treatments is crucial.

To prepare for ZINC implementation and discuss logistics, Morse and Paras Prasad, PhD, SUNY Distinguished Professor in the Departments of Chemistry, Physics, Medicine and Electrical Engineering and Samuel P. Capen Chair of Chemistry invited Professor Dzinotyiweyi to Western New York. “Professor Dzinotyiweyi’s visits to the ILPB, as well as the center, provided an opportunity for faculty leaders, regional scientists and public officials to discuss the recently announced international collaboration of UB and ZINC,” says Morse.

A public symposium will take place in Harare, Zimbabwe on March 18th and 19th. The symposium will include representatives from government, academia and the community. Meetings in Zimbabwe and Buffalo are scheduled to help all participants continue to get acquainted.

A future hope is to develop partnerships with pharmaceutical and biotechnology companies, drawing private-sector investments. In addition to that goal, a positive effect on economic development is expected to take place in Western New York and in Zimbabwe.

GO BNMC "GO Party" Member Appreciation Event!

February 18, 2013 by BNMCin Campus-wide, Employees, Event, Member Institution(s)1 Comment

GO BNMC members and employees on the BNMC are invited to attend the GO Party event, a member wp-contentreciation celebration full of fun activities, giveaways, food and drinks!
Learn about alternative commuting methods, mingle with GO BNMC Champions, and enjoy an evening of fun with fellow Medical Campus employees.

Sign-up to become a member of GO BNMC today at gobnmc-old.local. #GOParty on Twitter to @GOBNMC if you plan to attend and RSVP to gobnmc@bnmc-old.local.

Private Sector Investment on the Buffalo Niagara Medical Campus

February 12, 2013 by BNMCin Construction, Homepage, Investment Opportunities, Member Institution(s), News1 Comment

Post from Buffalo Niagara Enterprise Blog: Development Discussions
By Alan Rosenhoch, Business Development Manager, Buffalo Niagara Enterprise

Conventus rendering by Kideney Architects

Conventus (Latin for “coming together”) is a brand new seven-story medical building being developed by Ciminelli Real Estate Corporation at the northern gateway of the Buffalo Niagara Medical Campus (BNMC). Designed to be a center for collaborative medicine, it will be anchored by Kaleida Health and UBMD. Ciminelli expects to open the building in the spring of 2015.

I had the opportunity to ask the President and CEO of Ciminelli Real Estate Corporation, Paul F. Ciminelli, a few questions:

Q: You recently began site preparation work on the Conventus project; what does this project represent for the BNMC and the region’s life sciences industry?

A: There are two aspects of this project that represent major milestones in the development of the Medical Campus. First of all, Conventus is the first significant private investment on the campus, which is indicative of our strong commitment to the BNMC and our belief in its vision. Private dollars send a strong message to our community and to other markets that the Campus is a viable initiative and worth the investment.

Secondly, Conventus’ adjacency and physical connections to the new Children’s Hospital and the new UB School of Medicine, is groundbreaking in its collaborative wp-contentroach to the needs of the patients, physicians, researchers and students. Coupled with its location at the northern gateway to the Campus, Conventus facilitates a seamless connection among all of the major medical-related facilities at the northern end.

Q: How much space will be taken by the two anchor tenants, Kaleida and UBMD, and how much space will remain for future tenants?

A: Kaleida will occupy wp-contentroximately 85,000 sq. ft. on the 2^nd and 3^rd floors, which are the floors where connections will be made to Children’s and the Medical School, as well space on the ground floor for their Blood Draw and Pharmacy. UBMD will occupy 60,000 sq. ft. on the 4^th floor and a portion of the 5^th floor. A major regional bank will occupy a portion of the ground floor as well. Based on the inquiries we have had to date, we expect to have tremendous interest in the remaining square footage, and that full occupancy will be achieved quickly.

Q: What types of tenants are you seeking for the balance of space? For what type of company would you consider Conventus to be ideal space?

A: As with all of our projects, we will identify potential tenants that are synchronous with the existing tenant base and with the overall vision of the Campus. We refer to Conventus as a “center for collaborative medicine” because of the multiple disciplines that will be housed in and facilitated by our physical connections to the Hospital and UB’s School of Medicine. We look forward to accommodating clinical, educational, practical and research components at Conventus, as well as other healthcare-related tenants.

Q: You are targeting LEED Gold Certification for this project; why is sustainable design, building elements and operation so important to Ciminelli?

A: In 2008, Ciminelli made a commitment to pursue LEED certification with all of our projects going forward because of our commitment to minimizing our environmental footprint and to developing high-performing buildings. From an ownership standpoint, it has a definite positive impact on the long-term operating efficiencies of the building. From a tenant’s perspective, LEED certification translates to a healthier, more efficiently run environment in which to work. It’s a win-win.

Q: Conventus is not planned to be a one-shot project for Ciminelli on the BNMC; what else do you have on the drawing board for the near and long-term future?

A: The core of our business is being able to see the big picture; the ability to put pieces of a puzzle together and create synergies within every development project we undertake. This is what our company does best, and why we are committed to supporting the BNMC’s vision. We have purchased additional property at 33 High Street directly across from Conventus and Children’s Hospital and adjacent to UB’s site for the Medical School in anticipation of continued growth. As things continue to evolve on the Campus and we see possibilities for future needs there, we will pursue strategic developments to support those needs.

Q: Plans call for Conventus to connect to the Allen Street NFTA Metro Rail station; how does this fit into your overall plan to connect different parts of the region?

A: Ciminelli is a strong proponent of transit-oriented development, as evidenced by our two current projects under construction: Bethune Lofts (Main Street and Hertel Avenue), and Conventus. Developing along our transit lines facilitates connectivity among vibrant areas of Buffalo Niagara such as the UB South Campus University District, the Hertel Avenue district, the Medical Campus and Canalside. As it stands today, the NFTA Metro Rail station will be connected to the new UB School of Medicine at Allen Street. It should be noted that, while there is a connection from that building to Conventus, its use will be somewhat restricted.

Q: Conventus represents the first significant for-profit private sector-led development on the BNMC; what makes your company so bullish on the future of the campus?

A: Ciminelli has owned property on the Campus for 20 years, so we’ve been a part of it since its early stages. We saw things begin to evolve as the plan was rolled out. We’ve seen similar models succeed in cities of comparable size and demographics to Buffalo, so we knew it could work here, especially with it being so close to our Central Business District and being on a main transit line. All of the components were there; all it needed to take it to the next level was significant private sector investment. We were the first, but we know we won’t be the only ones. Additional private sector support will hwp-contenten on and around the Campus.

“My life works in Buffalo Niagara because of the tremendous quality of life we have in a relatively low-cost environment, the great educational institutions that supply a talented workforce, and because of the friendliness of its people. I love it here!”

– Paul F. Ciminelli

Business Sponsorships for GO BNMC Help Members Experience Surrounding Communities

February 11, 2013 by BNMCin Campus-wide, Community, Homepage, Wellness3 Comments

Support from local businesses in the area have poured in for GO BNMC, an initiative encouraging employees on the Buffalo Niagara Medical Campus (BNMC) to make healthier and sustainable transportation choices.
GO BNMC offers its members opportunities to enjoy the benefits of using alternative transportation methods, giving away rewards and incentives. When employees on the BNMC choose to bike, carpool, walk, take public transit or any other alternative mode to work, they walk the healthier walk and help to mitigate the amount of pollution released into the environment on a daily basis.

Follow @GOBNMC on Twitter for more news and updates.

May’s Monthly Smart Commuting Raffle & Incentives:

1 Gift Certificates to Oliver’s Restaurant

Free 30 Day Metro Pass

GO BNMC Sponsors:

Oliver’s Restaurant offers a wonderful decor and American and Italian food of excellent quality. A premier dining location, Oliver’s re-opened in 1983. Offering a delicious selection of wp-contentetizers, courses, wines and desserts, Oliver’s couples wonderful service with an aura of sophistication.

Betty’s Restaurant is located at 370 Virginia Street. Opening in October, 2004, Betty’s quickly won the hearts and loyalty of Buffalonians with its cheerful, sunny dining room, its friendly and funky staff, and its moderately priced eclectic cuisine. Betty’s food is simple, fresh, and creative, drawing on American and international influences, resulting in food that is wholesome, interesting, and unpretentious.

Located at 41 Virginia Place in Allentown, Fat Bob’s Smokehouse offers great service and our award-winning barbecue food. Authentic smoked meats straight from Fat Bob’s custom built Texas smoker, as well as traditional sides, seafood, wp-contentetizers, and desserts please every customer’s wp-contentetite. Fat Bob’s specializes in authentic barbecue and ice-cold beer.

Located at 33 Virginia Place, Mothers Restaurant main menu features wp-contentetizers such as steamed mussels with red curry and coconut milk broth or spaghetti squash with prosciutto, fresh sage and asiago cheese. Mothers serves unique salads, entrées and specials that are even more intriguing. Specials included two very interesting soups—curried shrimp and broccoli or tomato, sausage, and fennel. Appetizers and salads included freshly shucked Malpeque oysters on the half shell with cocktail and mignonette sauces or a salad of lump crab, avocado.

Located at 32 Allen Street, Madonna’s presents Italy on the plate and Buffalo in the heart. Madonna’s brings the Italian style of simple cooking and perfect ingredients to a city that embodies the same. With Italian style and Buffalo hospitality, this restaurant n Allentown is a great place to enjoy Italian cuisine.

The Dipson Theatres Market Arcade Film & Art Center is located in Downtown Buffalo, across from Shea’s Performing Arts Center. Showing the latest movies and offering concession items to help enjoy a great movie-going experience, the Market Arcade theater includes a cafe area and friendly service.

Located at 3 Symphony Circle, The Buffalo Philharmonic Orchestra provides a resident, professional, major symphony orchestra of artistic excellence and integrity to enrich the quality of life in Western New York through the presentation of live symphonic music and other musical events which educate and entertain the broadest po
ssible audiences within and beyond the Western New York region.

Located within the Hotel @ The Lafayette at 391 Washington Street, the Pan-American Grill & Brewery is a restaurant brewery with seating for 300-plus and a new mezzanine-level bar evoking the rich history of the former Lafayette Tap Room.

Located at 777 Main Street, Kaydara Noodle Bar is a restaurant that serves Vietnamese, Lao, Thai, Chinese, Korean and Japanese cuisine, including a centrally located 360 degree bar or seating overlooking the open kitchen or in the far corner with windows looking onto Main Street. Customers can also dine on the elevated platform or up in the balcony overlooking the Main Floor. Kaydara’s menu items include noodle-based dishes prepared in-house with a distinctive southeast Asian flare offering vegan and vegetarian options.

Located at 175 Allen Street in Allentown, Quaker Bonnet Eatery is the perfect spot for a breakfast meeting, brunch with friends, or lunch before a concert at nearby Kleinhans. Exhibits by local artists dot the walls, and Quaker Bonnet is a great source of information about cultural events in Western New York. All menu items and specials are available to enjoy at home. Specialty sandwiches, salads, soups, fresh pasta and potato salads daily specials (including hot entrees) & desserts are always available.

Tops Friendly Markets is a local grocery chain store that has grown since its establishment in the early 1920s. Located within every Buffalo neighborhood and throughout the region, Tops provides fresh produce, meat, seafood, baked goods, a carry-out cafe, deli and pharmacy services.

Located at 888 Main Street, Coco by Le Metro offers a variety of menu items including delicious sandwiches, soups, salads and more. Coco serves breakfast featuring fresh croissants, sfogliatelle pastries, breakfast focaccia, and egg sandwiches served on their heavenly English muffins, as well as coffee, tea and juice. Lunch features a full menu of salads, pasta dishes, sandwiches, burgers and more. Dinner is served with a basic dinner menu and changing seasonal dinner entrées.